801 Bourbon Bar

801 Bourbon Bar has been one of Key West's most celebrated nightlife destinations for decades, and one visit makes it immediately clear why. Perched at the iconic corner of 801 Duval Street and open daily from noon to 4 AM, this legendary LGBTQ nightclub is the home of the world-famous 801 Girls — a powerhouse drag troupe delivering jaw-dropping, high-energy performances nightly that have become a bucket-list experience for visitors from around the globe. Come for the shows, stay for the daily rotating specialty cocktails crafted fresh at the bar or mixed to your exact specs, and the kind of electric, anything-goes atmosphere that only Key West can produce. Whether it's karaoke night, bingo, a themed event, or just a Tuesday at midnight on Duval Street, the 801 always delivers — and with a TripAdvisor pedigree to match its legendary status, this is one stop you simply can't skip.